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How long does it take for losartan to get out of your system? Some people who struggle with substance abuse take Losartan to treat their high blood pressure. Losartan's terminal half-life is around two hours, and metabolite half-life is between six to nine hours. It should be out of your system roughly between 10 and 12 hours.
Can you take water pills at night? Diuretics, or " water - pills :" Take early in the day. If you need a second dose, take it by mid-afternoon to avoid extra trips to the bathroom at nighttime. Diuretics cause you to urinate more and can disrupt sleep if taken near bedtime. Taking blood pressure meds at night can decrease that risk.
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